孙伯禄,博士(后),副教授,硕士研究生导师,兰州理工大学“红柳优青”基金获得者,生命科学与工程学院制药工程专业教师。2014年6月本科毕业于兰州大学药学院药学专业,获理学学士。2020年6月博士毕业于兰州大学药学院药物化学生物学专业,获理学博士学位,师从兰州大学胡芳弟教授。2020年8月任职于兰州理工大学,2023年5月进入兰州理工大学材料科学与工程学院博士后流动站和兰州佛慈制药股份有限公司博士后工作站进行联合培养,合作导师孔令斌教授和胡芳弟教授。现主要从事(1)难诊性疾病(抑郁症、心脑血管疾病、睡眠障碍等)早期筛查诊断技术开发及应用研究;(2)中药质量(活性成分)快速评价及中药材(农作物)病害早期预警监测技术开发;(3)中药提取物活性筛选及相关大健康产品研发。目前在Biosensors and Bioelectronics、Matericals Science and Engineering C、Analytica Chimica Acta、 Bioelectrochemistry、Microchemical Journal等期刊以第一(或通讯)作者发表SCI论文20余篇,主持甘肃省自然科学基金1项,甘肃省教育厅高等学校创新基金项目1项,温州市科技计划项目1项,参与主持甘肃省药品安全监管科研项目1项,兰州市科技计划项目1项,参与科技部国家重点研发计划项目、国家自然科学基金面上项目、甘肃省重点项目10余项。获得甘肃省科技进步二等奖2项,长期担任多个SCI期刊审稿人。
一、 发表论文
2024年
1. Bolu Sun*, =, Liangrong Bao=, Yanlei Sun=, Jinhai Liu, Yuqiong Wu, Huajie Li, Shixing Yu, Yuhong Liu, Qiaoning Dang, Lin Yang*. Electrochemical immunosensor based on ferrocene derivatives amplified signal for detection of acute myocardial infarction warning biomarker-cTnI. Microchemical Journal, 2024. 199, 110057.
2. Bolu Sun #, *, Qiaoning Dang #, Chengyang Gao #, Hongxia Shi#, Quhuan Ma, Yuhong Liu, Shixing Yu, Liangrong Bao, Lin Yang*, Xiaofeng shi*. Ultrasensitive electrochemical immunosensor based on Fe3O4@g-C3N4 nanocomposites for detection of TCM root-rot early warning biomarker – zearalenone. Journal of Solid State Electrochemistry, 2024. https://doi.org/10.1007/s10008-024-05810-z.
2023年
1. Bolu Sun#*, Yanmei Yang#, Yanlei Sun#, Dan Wu, Lei Kan, Chengyang Gao, Hongxia Shi, Chunyan Sang, Tiankun Zhao, Lin Yang*, Quhuan Ma, Xiaofeng Shi*. Evaluating the antioxidant activity of secondary metabolites of endophytic fungi from Hypericum perforatum L. by an electrochemical biosensor based on AuNPs/AC@CS composite, Bioelectrochemistry. 2023, 151, 108400.
2. Bolu Sun#*, Lei Kan#, Chengyang Gao, Hongxia Shi, Lin Yang*, Tiankun Zhao, Quhuan Ma Xiaofeng Shi*, Chunyan Sang. Investigating immunosensor for determination of SD-biomarker-Aβ based on AuNPs/AC@PANI@CS modified electrodes with amplifying the signal. Analytical Biochemistry, 2023, 661: 114996.
3. Bolu Sun#*, Lei Kan#, Yuhong Liu#, Yanlei Sun#, Jinhai Liu, Yuqiong Wu, Huajie Li, Shixing Yu, Liangrong Bao, Chengyang Gao, Yanmei Yang, and Lin Yang. An electrochemical immunosensor based on GO@CS for highly sensitive and accurate detection of cardiovascular markers-cTn- I. Journal of The Electrochemical Society, 2023 (169) 087506.
4. Hong Wei, Bolu Sun, YuanYuan Li, Yanping Wang, Yan Chen, Min Guo, Xiaohui Mo, Fangdi Hu, Yongling Du. Electrochemical immunosensor AuNPs/NG‑PANI/ITO‑PET for the determination of BDNF in depressed mice serum. Microchimica Acta (2023) 190:330.
5. Bolu Sun#*, Yanmei Yang#, Shixing Yu, Liangrong Bao, Hongxia Shi, Qiaoning Dang, Yuhong Liu, Lin Yang*, Quhuan Ma, Xiaofeng Shi*. Electrochemical Biosensor Based on ds-DNA/N-G@CS/GCE for Highly Sensitive and Rapid Measurement of Antioxidant Activity. ECS Advances, 2023, 2, 026501.
2022年
1. Yanping Wang#, Bolu Sun#, Hong Wei, Yuanyuan Li, Fangdi Hu*, Xing Du*, Junhui Chen*. Investigating immunosensor for determination of depression Marker-Apo-A4 based on patterning AuNPs and N-Gr nanomaterials onto ITO-PET flexible electrodes with amplifying signal. Analytica Chimica Acta, 2022, (1224) 340217.
2. Bolu Sun#*, Chengyang Gao#, Lin Yang*, Hongxia Shi, Lei Kan, Quhuan Ma and Xiaofeng Shi*. A novel molecularly imprinted electrochemical sensor based on PANI@GO for highly sensitive and selective analysis of trace epigoitrin. Journal of The Electrochemical Society, 2022 (169) 087506.
3. Bolu Sun#*, Dan Wu#, Yanlei Sun#, Hongxia Shi, Lin Yang*, Chengyang Gao, Lei Kan, Quhuan Ma and Xiaofeng Shi*. Study and Application of Molecularly Imprinted Electrochemical Sensor Based on AuNPs/N-GR@CS for Highly Selective Recognition of Trace Hyperoside. ECS Advances, 2022, 1, 046503.
4. Jing Ma, Dai Li, Bolu Sun, Xiaohui Hou, Xinru Zhang-Peng, Wen Li, Yan Zhang, Fangdi Hu, Xiaofeng Shi. Label‐free Electrochemical Immunosensor for Sensitive Detection of Rheumatoid Arthritis Biomarker Anti‐CCP‐ab. Electroanalysis, 2022, 34, 761 –771.
2020年
1. Bolu Sun, Yanping Wang, Dai Li, Wuyan Li, Xiaodan Gou, Yuqiang Gou, Fangdi Hu*, Development of a sensitive electrochemical immunosensor using polyaniline functionalized graphene quantum dots for detecting a depression marker, Matericals Science and Engineering C, 2020, (111): 110797.
2. Bolu Sun, Dai Li, Xiaohui Hou, Wuyan Li, Yuqiang Gou, Fangdi Hu*, Wen Li*, Xiaofeng Shi*, A novel electrochemical immunosensor for the highly sensitive and selective detection of the depression marker human apolipoprotein A4, Bioelectrochemistry, 2020, (135): 107542. https://doi.org/10.1016/j.bioelechem.2020.107542.
2019年
1. Bolu Sun#, Dai Li#, Jinying Cai, Wuyan Li, Xiaodan Gou, Yuqiang Gou, Fangdi Hu⁎, An Electrochemical Sensor Based on Ultra-Micro Activated Carbon for the Determination of Puerarin, Journal of the Electrochemical Society, 2019, 166 (2) H33-H40.
2. Bolu Sun#, Chaoqun Wang#, Jinying Cai, Dai Li, Wuyan Li, Xiaodan Gou,Yuqiang Gou, Fangdi Hu⁎, Molecularly Imprinted Polymer-Nanoporous Carbon Composite-Based Electrochemical Sensor for Selective Detection of Calycosin, Journal of the Electrochemical Society, 2019, 166 (6) H187-H193.
3. Bolu Sun#, Xiaohui Hou#, Dai Li, Yuqiang Gou, Fangdi Hu*, Wen Li*, Xiaofeng Shi*, Electrochemical Sensing and High Selective Detection of Hesperidin with Molecularly Imprinted Polymer Based on Ultrafine Activated Carbon, Journal of the Electrochemical Society, 2019, 166 (15) B1644-B1652.
4. Jinying Cai#, Xiaodan Gou#, Bolu Sun, Wuyan Li, Dai Li, Jinglong Liu, Fangdi Hua∗, Yingdong Li∗, Porous graphene-black phosphorus nanocomposite modified electrode for detection of leptin, Biosensors and Bioelectronics, 2019, (137): 88–95.
5. Jinying Cai#, Bolu Sun#, Wuyan Li, Xiaodan Gou, Yuqiang Gou, Dai Li, Fangdi Hu*, Novel nanomaterial of porous graphene functionalized black phosphorus as electrochemical sensor platform for bisphenol A detection, Journal of Electroanalytical Chemistry, 2019, 835, 1–9.
6. Bolu Sun, Jinying Cai, Xiaodan Gou, Yuqiang Gou, Wen Li*, Fangdi Hu*. Fabrication of Electrochemical Sensor Modified with Porous Graphene for Determination of Trace Calycosin, Chinese Journal of Analytical Chemistry, 2019, 47(2): 271–280.
2018年
1. Bolu Sun, Jinying Cai, Wuyan Li, Xiaodan Gou, Yuqiang Gou, Dai Li, Fangdi Hu*, A novel electrochemical immunosensor based on PG for early screening of depression markers-heat shock protein 70, Biosensors and Bioelectronics, 2018, (111): 34–40.
2. Jinying Cai, Bolu Sun, Xiaodan Gou, Yuqiang Gou, Wen Li*, Fangdi Hu*. A novel way for analysis of calycosin via polyaniline functionalized graphene quantum dots fabricated electrochemical sensor, Journal of Electroanalytical Chemistry, 2018, (816): 123-131.
3. 马玉玲,郑晓萍, 孙伯禄,胡芳弟*. 复方党参口服液免疫增强作用的配伍相关性,中成药,2018, 40(4): 920-924.
2017年
1. Bolu Sun, Yuqiang Gou, Yuling Ma, Xiaoping Zheng, Ruibin Bai, Ahmed Attia Ahmed Abdelmoaty, Fangdi Hu*. Investigate electrochemical immunosensor of cortisol based on gold nanoparticles/magnetic functionalized reduced graphene oxide. Biosensors and Bioelectronics, 2017 (88):55-62.
2. Bolu Sun, Xiaodan Gou, Ruibin Bai, Ahmed Attia Ahmed Abdelmoaty, Yuling Ma, Xiaoping Zheng, Fangdi Hu*. Direct electrochemistry and electrocatalysis of lobetyolin via magnetic functionalized reduced graphene oxide/Nafion nanohybrid film fabricated electrochemical sensor. Matericals Science and Engineering C, 2017, 74: 515–524.
3. Pei Zhang, Lihai Hu, Rui-Bin Bai, Xiaoping Zheng, Yuling Ma, Xia Gao, Bo-Lu Sun, Fang-Di Hu. Structural characterization of a pectic polysaccharide from Codonopsis pilosula and its immunomodulatory activities in vivo and in vitro. International Journal of Biological Macromolecules. 2017, (104): 1359–1369.
4. Xiao-Ping Zheng, Fang-Di Hu, Li Yang, Yu-Ling Ma, Bo-Lu Sun, Chang-Hong Wang, Zheng-Tao Wang. The effects of different compatibility of Qing’e formula on scopolamine-induced learning and memory impairment in the mouse. World Journal of Traditional Chinese Medicine. 2017, 3(3):12-17.
5. 马玉玲,郑晓萍, 孙伯禄,胡芳弟*. 复方党参口服液的制备及免疫增强作用的实验研, 时珍国医国药, 2017, 28(9): 2142-2145.
6. 马玉玲, 郑晓萍, 孙伯禄,胡芳弟*.复方党参口服液的免疫增强功能研究. 中国药事, 2017(12):1488-1493.
7. 白瑞斌, 马玉玲, 郑晓萍, 孙伯禄,胡芳弟*. 基于纹党鲜药材的米炒饮片制备方法研究. 时珍国医国药, 2017(8):1881-1885.
2016年
1. Bolu Sun, Yuqiang Gou, Zhiyuan Xue, Xiaoping Zheng, Yuling Ma, Fangdi Hu*, Wanghong Zhao*. Protections of bovine serum albumin protein from damage on functionalized graphene-based electrodes by flavonoids. Materials Science and Engineering C, 2016, 62: 197–205.
2. Bolu Sun, Yuqiang Gou, Xiaoping Zheng, Yuling Ma, Fangdi Hu*. Electrochemical sensor for assessment of antioxidant activities of ferulic acid and extract in Angelica Sinensis based on DNA/NA-PDDA-G. Chinese Journal of Analytical Chemistry, 2016, 44(10):1575-1583.
3. Xia Gao, Yuling Ma, Pei Zhang, Xiaoping Zheng, Bolu Sun, Zhiyuan Xue, Fangdi Hu*. Chemical characteristics combined with bioactivity for comprehensive evaluation of Tumuxiang based on HPLC-DAD and multivariate statistical methods. World Journal of Traditional Chinese Medicine. 2016, DOI:10.15806/j.issn.2311-8571.2015.0035.
4. Pei Zhang, Yu-Qiang Gou, Xia Gao, Rui-Bin Bai, Wen-Xia Chen, Bo-Lu Sun, Fang-Di Hu*, Wang-Hong Zhao. The pharmacokinetic study of rutin in rat plasma based on an electrochemically reduced grapheme oxide modified sensor. Journal of Pharmaceutical Analysis, 2016, 6(2): 80-86.
5. 马玉玲, 薛志远, 高霞, 张培, 孙伯禄, 郑晓萍, 胡芳弟*.基于化学计量学的川木香抗炎活性朴硝关系研究.分析测试技术与仪器, 2016,22(1): 15-22.
二、获得奖励
(1) 孙伯禄(1/2); 抑郁症标志物及中药电活性成分分析新技术研究, 2018年中国药学会药物分析专业委员会学术委员会, 优秀论文奖, 其他, 2018(孙伯禄; 胡芳弟 ) (科研奖励)
(2) 孙伯禄(1/2); 抑郁症标志物分析新技术研究, 2017年第21届全国色谱学会, 优秀墙报奖, 其他, 2017(孙伯禄; 胡芳弟 ) (科研奖励)
(3) 孙伯禄(1/2); 中药及生物复杂样品分析新技术研究, 2017年第七届全国药物分析大会暨第三届药物分析国际论坛学术委员会, 优秀墙报奖, 其他, 2017(孙伯禄; 胡芳弟 ) (科研奖励)
(4) 孙伯禄(10/10); 天然党参多糖及其硒化物的制备、 活性研究及应用, 甘肃省人民政府, 科技进步,省部二等奖, 2017(胡芳弟; 陈嘉屿; 苟于强; 吴红梅; 胡林海; 贾孝荣; 杨春霞; 陈文霞; 张培; 孙伯禄)(科研奖励) 证书号:2016—J2—051—R10.
(5) 孙伯禄(10/15); 甘肃大宗道地药材产地加工炮制关键技术研究及应用, 甘肃省人民政府, 科技进步,省部二等奖, 2021(胡芳弟; 柴国林; 李文; 李晓东; 崔方; 孙科; 李芸; 白瑞斌; 王燕萍; 孙伯禄)(科研奖励) 获奖编号:2021—J2—020—R10.
三、 参与申请专利
1. 胡芳弟, 苟于强, 白瑞斌, 孙伯禄. 党参果胶多糖CPP1c的应用及其药物和保健品,专利号:201710002967.7
2. 胡芳弟, 白瑞斌, 王艳, 孙伯禄, 王燕萍, 苟于强. 一种含有党参低聚糖的钙奶片及其制备方法,申请号:202010134336.2(实审)
3. 胡芳弟, 张菊, 白瑞斌, 闫巧, 李雪, 樊精敏, 孙伯禄, 王燕萍, 张淹. 党参低聚糖在制备抗贫血药物中的应用,申请号:202010134418.7 (实审)
4. 胡芳弟, 闫巧, 苟于强, 白瑞斌, 李成楠, 孙伯禄, 王燕萍. 一种党参低聚糖固体饮料及其制备方法,申请号:202010134396.4 (实审)
5. 胡芳弟, 苟于强, 马玉玲, 白瑞斌, 孙伯禄. 一种具有促进免疫功能的复方药物及其制备方法, 申请号:201710067328.9(实审)
四、 参与出版专著
1. 胡芳弟, 崔方, 李文, 封士兰, 孙伯禄, 蔡金颖, 苟于强, 刘小花. 天然药物化学实验指导(英文版), 兰州大学出版社.
五、 参加学术活动情况
1. 免疫电化学与光谱电化学联用技术在抑郁症标志物分析中的应用,2019西部生命分析化学论坛,甘肃兰州
2. 三种抑郁症标志物分析的电化学传感技术研究,2019,中国化学会第十二届全国微全分析系统学术会议、第七届全国微纳尺度生物分离分析学术会议暨第七届国际微流控学学术论坛,陕西杨凌,口头报告
3. 抑郁症标志物及其相关药物分析的电化学传感技术研究,第二届中国化学快报分析化学前沿论坛会议,西藏灵芝
4. 抑郁症标志物及中药电活性成分分析新技术研究,2018年中国药学会药物分析专业委员会学术年会,陕西西安,口头报告
5. 中药及生物复杂样品分析新技术研究,第七届全国药物分析大会暨第三届药物分析国际论坛,辽宁沈阳,口头报告
6. 抑郁症标志物分析新技术研究,第21届全国色谱学术报告会及仪器展览会,甘肃兰州 海报展
7. 用于中药及生物复杂样品分析的传感器研究,2016全国生命分析学术会议,江苏南京,口头报告
8. 基于磁功能化还原氧化石墨烯的电化学传感器研究,中国化学会第30届学术年会,辽宁大连,口头报告
9. 2016兰州大学第九届学术年会药学院分论坛,甘肃兰州,口头报告
10. 2018兰州大学第十一届学术年会药学院分论坛,甘肃兰州,口头报告
六、 获得奖励列
1. 2023年“学习宣传贯彻党的二十大精神”教职工线上知识竞答活动二等奖
2. 2021年度甘肃省科技进步二等奖
3. 2021年“我心向党”青年教职工演讲比赛三等奖
4. 2020年兰州大学“百名学生党员标兵”称号
5. 2020年兰州大学2020届优秀毕业研究生
6. 2019年兰州大学第十二届学术年会药学院分论坛论文交流优秀奖
7. 2019年度兰州大学萃英榜样青年及第四届兰州大学十大“校园之星”候选人
8. 2019年度兰州大学三好研究生
9. 2019年度兰州大学“好医生”奖学金
10. 2018年度博士研究生国家奖学金
11. 2018年中国药学会药物分析专业委员会学术年会“普析通用杯”优秀论文奖
12. 2018年度兰州大学三好研究生
13. 2018年度兰州大学“坚守•奋斗”励志成长成才典型人物
14. 2018年兰州大学第五届“助学•筑梦•铸人”征文优秀奖
15. 2018年兰州大学第十一届学术年会药学院分论坛论文交流一等奖
16. 2018年度药学院优秀共产党员
17. 2017年第21届全国色谱学术报告会及仪器展览会优秀墙报奖
18. 2017年第七届全国药物分析大会暨第三届药物分析国际论坛优秀墙报奖
19. 2017年度药学院优秀共产党员
20. 2016年度硕士研究生国家奖学金
21. 2016年度甘肃省科技进步二等奖
22. 2016年度兰州大学“尚峰”校友奖学金
23. 2016年度兰州大学三好研究生
24. 2016年兰州大学第九届学术年会药学院分论坛论文交流一等奖
联系方式
通讯地址:兰州理工大学生命科学与工程学院(甘肃省兰州市七里河区彭家坪路36号)
邮编:730050
电话:+8618219816572(微信同号)
QQ:919709193
E-mail:sunbl14@lzu.edu.cn;sunbl@lut.edu.cn