郭晓鹏，男，理学博士。研究方向包括：（1）微生物菌种选育及相关方法学和机理研究；（2）根际和内生菌增强植物品质的微生态机制和分子机理；（3）微生态改良和生物修复相关的优良微生物创制。
研究结果：
[1] Guo XP, Zhang SL, Lei CR, Jia CL, Yin RS, Zhang MM, Liu W*, Lu D*. Oligotrophic state reduces the time dependence of the observed survival fraction for heavy ion beam-irradiated Saccharomyces cerevisiae and provides new insights into DNA repair. Applied and Environmental Microbiology 2024. DOI: 10.1128/aem.01113-24
[2] Guo XP, Li XE, Zhang SL, Zhu SH, Guo R, Gao Y, Wang YG*, Liu XF, Liu Y, Shi H. A joint analysis of metabolomics, network pharmacology, and molecular docking reveals the efficacy patterns in various medicinal segments of Angelica sinensis (Oliv.) Diels root. Journal of Food Biochemistry 2024. DOI: 10.1155/2024/7377627
[3] Jia CL, Chai R, Zhang MM, Guo XP*, Zhou X, Ding N, Lu D*. Improvement of Saccharomyces cerevisiae strain tolerance to vanillin through heavy ion radiation combined with adaptive laboratory evolution. Journal of Biotechnology 2024, 394: 112-124. DOI:10.1016/j.jbiotec.2024.08.014
[4] Ren JL, Zhang MM, Guo XP*, Zhou X, Ding N, Lei CR, Jia CL, Wang YJ, Zhao JR, Dong ZY, Lu D*. Furfural tolerance of mutant Saccharomyces cerevisiae selected via ionizing radiation combined with adaptive laboratory evolution. Biotechnology for Biofuels and Bioproducts 2024, 17(1):117. DOI:10.1186/s13068-024-02562-w
[5] Lei CR, Guo XP*, Zhang MM*, Zhou X, Ding N, Ren JL, Liu MH, Jia CL, Wang YJ, Zhao JR, Dong ZY, Lu D*. Regulating the metabolic flux of pyruvate dehydrogenase bypass to enhance lipid production in Saccharomyces cerevisiae. Communications Biology 2024. DOI: 10.1038/s42003-024-07103-7.
[6] Sun Y, Guo R, Geng YT, Shang HS, Guo XP*, Wu Y, Wang YG*, Li L, Li XE, Zhang SL, Xu N, Li XY. Longitudinal Distribution Map of the Active Components and Endophytic Fungi in Angelica sinensis (Oliv.) Diels Root and Their Potential Correlations. Metabolites 2024, 14(1): DOI: 10.3390/metabo14010048
[7] Guo XP, Ren JL, Zhou X, Zhang MM, Lei CR, Chai R, Zhang LX, Lu D. Strategies to improve the efficiency and quality of mutant breeding using heavy-ion beam irradiation. Critical Reviews in Biotechnology 2023, 44(5): 735-752. DOI: 10.1080/07388551.2023.2226339
[8] Sun Y, Liu MH, Lu D, Wang YM, Li L, Wu Y, Zhang LX, Xv QK, Li RQ, Liu TY, Lu T, Guo ZH, Guo XP*. Large-scale microbiome analysis reveals bacterial community characteristics in typical Chinese herbal slices. Biologia 2022, 77(12): 3565-3580. DOI: 10.1007/s11756-022-01199-0
[9] Guo XP, Zhang MM, Gao Y, Lu D, Li WJ, Zhou LB. Repair characteristics and time-dependent effects in response to heavy-ion beam irradiation in Saccharomyces cerevisiae: a comparison with X-ray irradiation. Applied Microbiology and Biotechnology 2020, 104(9): 4043-4057. DOI: 10.1007/s00253-020-10464-8
[10] Guo XP, Zhang MM, Gao Y, Cao GZ, Lu D, Li WJ. Quantitative multi-omics analysis of the effects of mitochondrial dysfunction on lipid metabolism in Saccharomyces cerevisiae. Applied Microbiology and Biotechnology 2020, 104(3): 1211-1226. DOI: 10.1007/s00253-019-10260-z
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