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赵洪源
2023-08-11 点击: 作者: 来源:

赵洪源,工学博士,讲师。2023年06月毕业于南京农业大学食品科技学院酶工程实验室。参与国家自然科学基金面上项目1项,国家自然科学基金地区科学基金项目1项,以参与人身份获河南省科学技术进步二等奖。以第一作者在Pharmacological research, Food & function, Food Science and Human Wellness等期刊发表文章6篇,其中2023年ESI高被引文章1篇,另参与发表论文20余篇。主要研究方向是功能性食品,开展优质益生菌的筛选和功能成分的分离纯化,并探究益生菌和功能性成分对代谢型疾病的调节机制。

一、 主持或参与的科研项目

1. 兰州理工大学红柳优秀青年人才支持计划(第五批),在研,主持;

2. 兰州理工大学博士科研启动基金,202312月立项,在研,主持;

3. 甘肃省2023年知识产权运用项目,202312月立项,在研,主持。

二、 代表性成果

1. Zhao Hongyua, Lu Zhaoxin, Lu Yingjian. The potential of probiotics in the amelioration of hyperuricemia[J]. Food & function, 2022, 13(5): 2394-2414. (高被引文章)(中科院一区)

2. Zhao Hongyuan, Chen Xiaoyu, Meng Fanqiang, Zhou Libang, Pang Xinyi, Lu Zhaoxin, Lu Yingjian. Ameliorative effect of Lacticaseibacillus rhamnosus Fmb14 from Chinese yogurt on hyperuricemia[J]. Food Science and Human Wellness, 2023, 12(4): 1379-1390. (中科院一区)

3. Zhao Hongyuan, Chen Xiaoyu, Zhang Li, Tang Chao, Meng Fanqiang, Zhou Libang, Zhu Ping, Lu Zhaoxin, Lu Yingjian. Ingestion of Lacticaseibacillus rhamnosus Fmb14 prevents depression-like behavior and brain neural activity via the microbiota-gut-brain axis in colitis mice[J]. Food & function, 2023, 14(4): 1909-1928. 中科院一区

4. Zhao Hongyuan, Chen Xiaoyu, Zhang Li, Meng Fanqiang, Zhou Libang, Pang Xinyi, Lu Zhaoxin, Lu Yingjian. Lacticaseibacillus rhamnosus Fmb14 prevents purine induced hyperuricemia and alleviate renal fibrosis through gut-kidney axis[J]. Pharmacological research, 2022: 106350. (中科院一区)

5. Zhao Hongyuan, Chen Xiaoyu, Zhang Li, Meng Fanqiang, Zhou Libang, Zhu Ping, Lu Zhaoxin, Lu Yingjian.  Lacticaseibacillus rhamnosus Fmb14 ameliorates hyperuricemia-induced hepatocyte pyroptosis via NLRP3 inflammasome cascade Inhibition[J]Food Science and Human Wellness (Accepted). (中科院一区)

6. Zhao Hongyuan and Yun Jianmin, Isolation, identification and fermentation conditions of highly acetoin-producing acetic acid bacterium from Liangzhou fumigated vinegar in China[J] . Annals of Microbiology, 2016, 66(1):279-288.( 中科院四区,)

7. Tang Chao, Zhao Hongyuan, Kong Liangyu, Meng Fanqiang, Zhou Libang, Lu Zhaoxin, Lu Yingjian. Probiotic Yogurt Alleviates High-Fat Diet-Induced Lipid Accumulation and Insulin Resistance in Mice via the Adiponectin Pathway[J]. Journal of Agricultural and Food Chemistry, 2023, 71(3): 1464-1476. (共同一作)(中科院一区)

8. Chen Xiaoyu, Zhao Hongyuan, Lu Yajun, Liu Huawei, Meng Fanqiang, Lu Zhaoxin, Lu Yingjian. Surfactin Mitigates a High-Fat Diet and Streptozotocin-Induced Type 2 Diabetes through Improving Pancreatic Dysfunction and Inhibiting Inflammatory Response[J]. International Journal of Molecular Sciences, 2022, 23(19). (中科院二区)

9. Chen Xiaoyu, Zhao Hongyuan, Lu Yajun, Meng Fanqiang, Lu Zhaoxin, Lu Yingjian. Surfactin Mitigates Dextran Sodium Sulfate-Induced Colitis and Behavioral Disorders in Mice by Mediating Gut-Brain-Axis Balance[J]. Journal of Agricultural and Food Chemistry, 2023. (中科院一区)

10. Chen X, Zhao H, Meng F, et al. Ameliorated effects of a lipopeptide surfactin on insulin resistance in vitro and in vivo[J]. Food Science & Nutrition, 2022, 10(7): 2455-2469. (中科院三区)

11. Chen Xiaoyu, Lu Yajun, Shan Mengyuan, Zhao Hongyuan, Lu Zhaoxin, Lu Yingjian. A mini-review: mechanism of antimicrobial action and application of surfactin[J]. World Journal of Microbiology & Biotechnology, 2022, 38(8). (中科院三区)

12. Meng Fanqiang, Lyu Yunbin, Zhao Hongyuan, Lyu Fengxia, Bie Xiaomei, Lu Yingjian, Chen Yihua, Lu Zhaoxin. LsrR-like protein responds to stress tolerance by regulating polysaccharide biosynthesis in Lactiplantibacillus plantarum[J]. International Journal of Biological Macromolecules, 2023, 225: 1193-1203. (中科院一区)

13. Chen Xiaoyu, Zhao Hongyuan, Meng Fanqiang, Zhou Libang, Lu Zhaoxin, Lu Yingjian. Surfactin alleviated hyperglycaemia in mice with type 2 diabetes induced by a high-fat diet and streptozotocin. Food Science and Human Wellness. 2023Accepted)(中科院一区)

14. 赵洪源,贠建民,邵晓庆,.凉州熏醋酿造中高产乙偶姻醋酸菌株筛选及其发酵条件优化[J].食品科学,2015,36(15):98-104.

15. 陆兆新,赵洪源,吕凤霞,别小妹,赵海珍. 具有预防或缓解高尿酸血症的鼠李糖乳杆菌fmb14及应用[P]. 江苏省:CN114574382A,2022-06-03. (第二发明人,导师第一)

三、 联系方式

通讯地址:兰州理工大学生命科学与工程学院(兰州市七里河区彭家坪路36号)

邮政编码:730050

电子邮箱:20230064@lut.edu.cn; 31593229@163.com

QQ: 31593229